Dodola

Contributors: Ernest Mordret

Description

Dodola is named after a figure from Slavic mythology, often associated with rain and fertility. The Dodola defense system was first discovered through its common association with known defense systems, and characterized in B. subtilis, demonstrating its efficacy against the SPP1 phage (N/A) . Dodola is composed of two proteins, DolA and DolB. DolA contains a DUF6414 domain, and DolB contains a ClpB-like domain.

Molecular mechanisms

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The Dodola is composed of 2 proteins: DolA and DolB.

Here is an example found in the RefSeq database:

dodola

The Dodola system in Lacrimispora saccharolytica (GCF_000144625.1, NC_014376) is composed of 2 proteins DolA (WP_012104148.1) DolB (WP_012104147.1)

Distribution of the system among prokaryotes

Structure

Experimental validation