FS_Sma
Contributors: Héloïse Georjon
Description
SMA (single-protein MazF-like antiphage system) was identified in a phage-inducible chromosomal island (PICI) found in Staphylococcus aureus (N/A) . SMA was shown to inhibit phage infection and to inhibit the formation of new virions after prophage induction.
Molecular mechanisms
The SMA protein comprises a domain analogous to MazF. MazF is a protein that is normally part of the MazEF toxin-antitoxin systems, in which MazF is a toxic endoribonuclease that targets mRNA (N/A) . As far as we are aware, the precise molecular mechanism of SMA is unknown.
Example of genomic structure
The Sma is composed of 1 protein: Sma.
Here is an example found in the RefSeq database:
The Sma system in Staphylococcus aureus (GCF_022869625.1, NZ_CP064365) is composed of 1 protein: Sma (WP_000041883.1)