ApeA

Contributors: Hugo Vaysset

Description

ApeA is a defense system composed of one protein, initially described as a member of the HEPN superfamily which groups proteins with nucleotide binding activity (CL0291).

ApeA is predicted to act via an abortive infection mechanism.

Molecular mechanism

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The Gao_Ape is composed of 1 protein: ApeA.

Here is an example found in the RefSeq database:

gao_ape

The Gao_Ape system in Enterobacter mori (GCF_018638795.1, NZ_CP071064) is composed of 1 protein: ApeA (WP_215231222.1)

Distribution of the system among prokaryotes

Structure

Experimental validation