PD-T4-8

Description

PD-T4-8 is composed of a single protein that contains a DUF4263 domain found in the Shedu defense system (N/A) . PD-T4-8 from Escherichia coli RCP52534.1 confers resistance against T2, T4, T6, SECphi18 and SECphi27.

Molecular mechanisms

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The PD-T4-8 is composed of 1 protein: PD-T4-8.

Here is an example found in the RefSeq database:

The PD-T4-8 system in Algoriphagus sp. Y33 (GCF_014838715.1, NZ_CP061947) is composed of 1 protein: PD-T4-8 (WP_144603961.1)

Distribution of the system among prokaryotes

Structure

Experimental validation

      
graph LR;
    Vassallo_2022[Vassallo et al., 2022] --> Origin_0
    Origin_0[Escherichia coli 
RCP52534.1] --> Expressed_0[Escherichia coli]
    Expressed_0[Escherichia coli] ----> T2 & T4 & T6 & SECphi18 & SECphi27
    subgraph Title1[Reference]
        Vassallo_2022
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        T2
        T4
        T6
        SECphi18
        SECphi27
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none