PD-T7-5
Contributors: Hugo Vaysset
Description
PD-T7-5 is a defense system composed of a single protein which was discovered in (N/A) . Its antiphage activity was assessed by heterologous expression in E. coli against T7 and to reduce the size of lysis plaques of T3 (N/A) . PD-T7-5 contains a PD(D/E)XK nuclease domain like PD-T7-1.
Molecular mechanism
As far as we are aware, the molecular mechanism is unknown. However, the presence of a PD(D/E)XK domain in PD-T7-5 suggests a mechanism of action via DNA degradation (N/A) .
Example of genomic structure
The PD-T7-5 system is composed of one protein: PD-T7-5.
Here is an example found in the RefSeq database:
The PD-T7-5 system in Shewanella putrefaciens (GCF_019599085.1, NZ_CP080633) is composed of 1 protein: PD-T7-5 (WP_220590848.1)