AbiL
Description
AbiL was discovered in Lactococcus lactis. A plasmid containing the defense system was found to prevent infection by phage 712 through an abortive infection system
Molecular mechanism
Abortive infection. the PF13707 domain includes the RloB protein that is found within a bacterial restriction-modification operon. This family includes the AbiLii protein that is found as part of a plasmid-encoded phage abortive infection mechanism. Deletion within abiLii abolished the phage resistance. The family includes some proteins annotated as CRISPR Csm2 proteins.
Example of genomic structure
The AbiL is composed of 2 proteins: AbiLi and AbiLii.
Here is an example found in the RefSeq database:
The AbiL system in Sulfurimonas sp. SWIR-19 (GCF_020410885.1, NZ_CP084578) is composed of 2 proteins AbiLi2 (WP_226066409.1) AbiLii2 (WP_226066410.1)