PD-T4-3
Contributors: Ernest Mordret
Description
PD-T4-3 is a single gene system isolated during an experimental screen of fosmids derived from 71 strains of diverse E.coli, and cloned back in a derivative of K12. Fragments containing the PD-T4-3 gene were shown to provide resistance to phage T4. The protein is characterized by a GIY-YIG nuclease domain, and mutations inactivating this domain abolished the resistance phenotype. It was originally found on a µ-like prophage
Molecular mechanism
the molecular mechanism of this system is unknown
Example of genomic structure
The PD-T4-3 is composed of 1 protein: PD-T4-3.
Here is an example found in the RefSeq database:
The PD-T4-3 system in Morganella morganii (GCF_018802485.1, NZ_CP064826) is composed of 1 protein: PD-T4-3 (WP_214179544.1)