PD-T4-4
Contributors: Nathalie Bechon
Description
PD-T4-4 is a defense system composed of two proteins, a P-loop NTPase and a nuclease, that is most likely protecting the bacterial population through abortive infection. It was identified from an ICE in an E. coli genome.
Molecular mechanisms
PD-T4-4 molecular mechanism is currently unknown, although it is most likely an abortive infection system.
Example of genomic structure
The PD-T4-4 is composed of 2 proteins: PD-T4-4_A and PD-T4-4_B.
Here is an example found in the RefSeq database:
The PD-T4-4 system in Thiothrix subterranea (GCF_016772315.1, NZ_CP053482) is composed of 2 proteins PD-T4-4_A (WP_202716711.1) PD-T4-4_B (WP_202716712.1)