AbiR

Contributors: Florian Tesson

Description

AbiR is a defense system discovered in 2000 (N/A) .

AbiR is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry (N/A) . AbiR is classified as abortive infection in (N/A) .

AbiR is composed of 3 genes: AbiRa, AbiRb, AbiRc. AbiRa encodes a sigma70 RNA polymerase subunit. AbiRb as homology with ParB nuclease domain according to HHpred. AbiRc has two different domains: an N_terminal PLD domain (PF13091) and at the C term an SNF2 DNA-dependent ATPase.

Molecular mechanism

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The AbiR is composed of 3 proteins: AbiRa, AbiRb and AbiRc.

Here is an example found in the RefSeq database:

abir

The AbiR system in Clostridium perfringens (GCF_016027155.1, NZ_CP065677) is composed of 3 proteins AbiRc (WP_049039794.1) AbiRb (WP_049039795.1) AbiRa (WP_049039796.1)

Distribution of the system among prokaryotes

Structure

Experimental validation