AbiT

Description

AbiT was discovered in Lactococcus lactis in 2022 (N/A) .

AbiT is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry (N/A) . Even though, their name corresponds to abortive infection, their mechanism of action does not necessarily correspond to an abortive infection phenotype. AbiT is classified as an abortive infection in (N/A) .

AbiT is composed of two proteins: AbiTi with a transmembrane helix domain and AbiTii.

Molecular mechanism

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The AbiT is composed of 2 proteins: AbiTi and AbiTii.

Here is an example found in the RefSeq database:

The AbiT system in Bdellovibrio bacteriovorus (GCF_000317895.1, NC_019567) is composed of 2 proteins AbiTii (WP_051026283.1) AbiTi (WP_041577337.1)

Distribution of the system among prokaryotes

Structure

Experimental validation

      
graph LR;
    Chopin_2005[Chopin et al., 2005] --> Origin_0
    Origin_0[lactococcal plasmid 
AAN60762.1, AAN60763.1] --> Expressed_0[lactococci]
    Expressed_0[lactococci] ----> 936 & P335
    subgraph Title1[Reference]
        Chopin_2005
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        936
        P335
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none