AbiZ

Description

AbiZ was discovered in 2006 on a Lactococcus lactis conjugative plasmid pTR2030 (N/A) .

AbiZ is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry (N/A) . AbiZ is classified as abortive infection in (N/A) .

AbiZ is composed of a single protein AbiZ.

Molecular mechanism

AbiZ acts as an abortive infection system. AbiZ proteins sense holins and lysins from the infecting bacteriophage and use them to induce premature cell lysis (N/A, N/A) .

Example of genomic structure

The AbiZ is composed of 1 protein: AbiZ.

Here is an example found in the RefSeq database:

The AbiZ system in Fusobacterium pseudoperiodonticum (GCF_002763695.1, NZ_CP024700) is composed of 1 protein: AbiZ (WP_099987858.1)

Distribution of the system among prokaryotes

Structure

Experimental validation

      
graph LR;
    Durmaz_2007[Durmaz and  Klaenhammer, 2007] --> Origin_0
    Origin_0[Lactococcus lactis 
ABI93964.1] --> Expressed_0[Lactococcus lactis]
    Expressed_0[Lactococcus lactis] ----> Phi31.2 & ul36 & phi31 & phi48 & phi31.1 & Q30 & Q36 & Q33 & phi50 & phi48
    subgraph Title1[Reference]
        Durmaz_2007
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        Phi31.2
        ul36
        phi31
        phi48
        phi31.1
        Q30
        Q36
        Q33
        phi50
        phi48
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none