PD-T4-10
Contributors: Alba Herrero del Valle
Description
The PD-T4-10 system is composed of 2 proteins: PD-T4-10_B and, PD-T4-10_A. These ORFs are overlapping and PD-T4-10_B is toxic while PD-T4-10_A neutralizes its toxicity, hinting at a toxin-antitoxin (TA) mechanism. It confers resitance to T2, T4, T6 and SECphi27 through an Abi defense mechanism (N/A) .
Molecular mechanism
As far as we are aware, the molecular mechanism is unknown.
Example of genomic structure
The PD-T4-10 is composed of 2 proteins: PD-T4-10_A and PD-T4-10_B.
Here is an example found in the RefSeq database:
The PD-T4-10 system in Escherichia fergusonii (GCF_019047545.1, NZ_CP077242) is composed of 2 proteins PD-T4-10_A (WP_032236482.1) PD-T4-10_B (WP_032236481.1)