AbiC

Description

AbiC was discovered in Lactococcus lactis plasmid in 1992 (N/A)

AbiC is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry (N/A) . AbiC is classified as abortive infection in (N/A) .

AbiC is a single gene system composed of the protein AbiC.

Molecular mechanism

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The AbiC is composed of 1 protein: AbiC.

Here is an example found in the RefSeq database:

The AbiC system in Cupriavidus pauculus (GCF_008693385.1, NZ_CP044066) is composed of 1 protein: AbiC (WP_150373977.1)

Distribution of the system among prokaryotes

Structure

Experimental validation

      
graph LR;
    Fillol-Salom_2022[Fillol-Salom et al., 2022] --> Origin_0
    Origin_0[Klebsiella pneumoniae's  PICI KpCIFDAARGOS_1313 
QRS09118.1] --> Expressed_0[Escherichia coli]
    Expressed_0[Escherichia coli] ----> T5 & Lambda & HK97 & HK544 & HK578 & T7
    Fillol-Salom_2022[Fillol-Salom et al., 2022] --> Origin_0
    Origin_0[Klebsiella pneumoniae's  PICI KpCIFDAARGOS_1313 
QRS09118.1] --> Expressed_1[Salmonella enterica]
    Expressed_1[Salmonella enterica] ----> P22 & BTP1 & ES18
    Fillol-Salom_2022[Fillol-Salom et al., 2022] --> Origin_0
    Origin_0[Klebsiella pneumoniae's  PICI KpCIFDAARGOS_1313 
QRS09118.1] --> Expressed_2[Klebsiella pneumoniae]
    Expressed_2[Klebsiella pneumoniae] ----> Pokey & Raw & Eggy
    Chopin_2005[Chopin et al., 2005] --> Origin_1
    Origin_1[lactococcal plasmid 
AAA53569.1] --> Expressed_3[lactococci]
    Expressed_3[lactococci] ----> 936 & P335
    subgraph Title1[Reference]
        Fillol-Salom_2022
        Chopin_2005
end
    subgraph Title2[System origin]
        Origin_0
        Origin_0
        Origin_0
        Origin_1
end
    subgraph Title3[Expression species]
        Expressed_0
        Expressed_1
        Expressed_2
        Expressed_3
end
    subgraph Title4[Protects against]
        T5
        Lambda
        HK97
        HK544
        HK578
        T7
        P22
        BTP1
        ES18
        Pokey
        Raw
        Eggy
        936
        P335
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none