GAPS1
Description
The GAPS1 system is composed of a single protein. It was found in Gamma-Mobile-Trio (GMT) protein containing genomic island in Vibrio, and cloned into E. coli K-12 (N/A) . The name GAPS derives from the "GMT-encoded Anti-Phage System" acronym. GAPS1 contains a predicted nuclease domain whose mutation prevents defense activity, however DNA degradation was not detected in targeted phage (N/A) . Mutations in the folded capsid protein (Gp10) of phage T7 result in an escape phenotype, with GAPS1 shown to be activated upon Gp10 expression, suggesting activation of the system at late stages of the infection cycle (N/A) .
Molecular mechanisms
The molecular mechanism remains to be fully elucidated.
Example of genomic structure
The GAPS1 is composed of 1 protein: GAPS1.
Here is an example found in the RefSeq database:
The GAPS1 system in Hydrogenophaga sp. BPS33 (GCF_009859475.1, NZ_CP044549) is composed of 1 protein: GAPS1 (WP_159591124.1)