AbiP2
Description
AbiP2 system was discovered in 2006 inside a variable region of the P2-like coliphages (N/A) . This paper shows a relation with the known "Abi" system AbiK.
It was then proven to have an antiphage activity against T5 in E. coli (N/A) .
AbiP2 is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry (N/A) . AbiP2 is classified as possible abortive infection in (N/A) .
This system is called AbiP2 for the P2-like phage and has no relation with AbiP (a homolog of AbiC](/defense-systems/abic)).
However, with the discovery of dozens of new systems, it was categorized as one of the UG/Abi defense systems (N/A) along with DRT different subsystems, AbiA, AbiK and Rst_RT_Nitralase_TM.
Those systems are characterized by the presence of a reverse transcriptase domain of the "Unknown Group RT".
Molecular mechanism
To our knowledge, the molecular mechanism is unknown. Similarly, for the other systems of this family, the molecular mechanism remains unknown.
Example of genomic structure
The AbiP2 is composed of 1 protein: AbiP2.
Here is an example found in the RefSeq database:
The AbiP2 system in Halomonas alkaliphila (GCF_003612795.1, NZ_CP024811) is composed of 1 protein: AbiP2 (WP_120386816.1)