Rst_gop_beta_cll

Contributors: Florian Tesson

Description

The gop-beta-cll system was shown to have an antiphage activity in 2022 (N/A) against Escherichia coli phage lambda and P1.

The gop-beta-cll was first described as a nonessential region of the bacteriophage P4 (N/A) .

This system is composed of 3 genes: gop, beta and cll.

Molecular mechanism

As far as we are aware, the molecular mechanism is unknown.

The production of the gop protein without beta is toxic (N/A) suggesting a toxin antitoxin mechanism (N/A) .

Example of genomic structure

The Rst_gop_beta_cll is composed of 3 proteins: beta, cll and gop.

Here is an example found in the RefSeq database:

rst_gop_beta_cll

The Rst_gop_beta_cll system in Klebsiella grimontii (GCF_019334465.1, NZ_CP079754) is composed of 3 proteins gop (WP_189095150.1) beta (WP_189095151.1) cll (WP_219192256.1)

Distribution of the system among prokaryotes

Structure

Experimental validation