GAPS2

Contributors: Florian Tesson

Description

The GAPS2 system is composed of a single protein. It was found in Gamma-Mobile-Trio (GMT) protein containing genomic island in Vibrio, and cloned into E. coli K-12 (N/A) . The name GAPS derives from the "GMT-encoded Anti-Phage System" acronym.

GAPS2 is composed of a single protein with a DNA BRCT domains (N/A) .

Molecular mechanisms

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The GAPS2 is composed of 1 protein: GAPS2.

Here is an example found in the RefSeq database:

The GAPS2 system in Mannheimia sp. USDA-ARS-USMARC-1261 (GCF_000521605.1, NZ_CP006942) is composed of 1 protein: GAPS2 (WP_025236539.1)

Distribution of the system among prokaryotes

Among the NaN complete genomes of RefSeq, the GAPS2 is detected in NaN genomes (NaN %). The system was detected in NaN different species.
phylum
Percent genome having the system
0
100
Minimum genomes count to display

Structure

Summary
Group
Structure
Foldseek
System
Gene name
Subtype
Proteins in structure
System genes
Prediction type
N genes in sys
pLDDT
iptm+ptm
pDockQ
No data available

Experimental validation

      
graph LR;
    Mahata_2023[Mahata et al., 2023] --> Origin_0
    Origin_0[Vibrio parahaemolyticus 
WP_174208646.1] --> Expressed_0[Escherichia coli]
    Expressed_0[Escherichia coli] ----> P1-vir & Lambda-vir
    subgraph Title1[Reference]
        Mahata_2023
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        P1-vir
        Lambda-vir
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none