AbiQ

Description

AbiQ was discovered in 1998 on Lactococcus lactis plasmid (N/A) .

AbiQ is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry (N/A) . AbiQ is classified as abortive infection in (N/A) .

AbiQ is composed of a single protein AbiQ and an RNA antitoxin (antiQ) (N/A) .

Molecular mechanism

AbiQ act as an anti-toxin type III. AbiQ is an RNAase that will bind its antitoxin antiQ (N/A) .

The AbiQ is constitutively expressed and bind to its antiQ RNA resulting in an inactivated AbiQ. To get activated, AbiQ needs the concentration of antiQ to decrease. However, during phage infection, the expression of the antiQ is constant and the authors do not know how the AbiQ is activated (N/A) .

Example of genomic structure

The AbiQ is composed of 1 protein: AbiQ.

Here is an example found in the RefSeq database:

The AbiQ system in Planococcus faecalis (GCF_002009235.1, NZ_CP019401) is composed of 1 protein: AbiQ (WP_078080483.1)

Distribution of the system among prokaryotes

Structure

Experimental validation

      
graph LR;
    Chopin_2005[Chopin et al., 2005] --> Origin_0
    Origin_0[lactococcal plasmid 
AAC98713.1] --> Expressed_0[lactococci]
    Expressed_0[lactococci] ----> 936 & c2
    subgraph Title1[Reference]
        Chopin_2005
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        936
        c2
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none