AbiQ

Contributors: Florian Tesson

Description

AbiQ was discovered in 1998 on Lactococcus lactis plasmid (N/A) .

AbiQ is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry (N/A) . AbiQ is classified as abortive infection in (N/A) .

AbiQ is composed of a single protein AbiQ and an RNA antitoxin (antiQ) (N/A) .

Molecular mechanism

AbiQ act as an anti-toxin type III. AbiQ is an RNAase that will bind its antitoxin antiQ (N/A) .

The AbiQ is constitutively expressed and bind to its antiQ RNA resulting in an inactivated AbiQ. To get activated, AbiQ needs the concentration of antiQ to decrease. However, during phage infection, the expression of the antiQ is constant and the authors do not know how the AbiQ is activated (N/A) .

Example of genomic structure

The AbiQ is composed of 1 protein: AbiQ.

Here is an example found in the RefSeq database:

abiq

The AbiQ system in Planococcus faecalis (GCF_002009235.1, NZ_CP019401) is composed of 1 protein: AbiQ (WP_078080483.1)

Distribution of the system among prokaryotes

Structure

Experimental validation