AbiG

Contributors: Florian Tesson

Description

AbiG was discovered in 1996 on the plasmid pCI750 of Lactococcus lactis () .

AbiG is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry () . AbiG is classified as abortive infection in () .

AbiG is composed of two genes AbiGi and AbiGii.

Molecular mechanism

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The AbiG is composed of 2 proteins: AbiGi and AbiGii.

Here is an example found in the RefSeq database:

The AbiG system in Staphylococcus simulans (GCF_900474685.1, NZ_LS483313) is composed of 2 proteins AbiGi (WP_103364194.1) AbiGii (WP_070462993.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the AbiG is detected in 32 genomes (0.14 %).

The system was detected in 22 different species.

Proportion of genome encoding the AbiG system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

AbiG

Example 1

Experimental validation

      
graph LR;
    Chopin_2005[Chopin et al., 2005] --> Origin_0
    Origin_0[lactococcal plasmid 
AAB38312.1, AAB38313.1] --> Expressed_0[lactococci]
    Expressed_0[lactococci] ----> 936 & c2 & P335
    subgraph Title1[Reference]
        Chopin_2005
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        936
        c2
        P335
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none

    

References

10.1023/A:1002027321171
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10.1016/j.mib.2005.06.006
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10.1128/aem.62.9.3075-3082.1996
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10.1016/j.mib.2023.102312
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