AbiH

Contributors: Florian Tesson

Description

AbiH a system discovered in 1996 () .

AbiH is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry () . Even though, their name corresponds to an abortive infection, their mechanism of action does not necessarily correspond to an abortive infection. For the abortive infection, phenotype AbiH is classified as unknown in () .

This system is a single gene system with no known domain (except its own PFAM).

Molecular mechanism

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The AbiH is composed of 1 protein: AbiH.

Here is an example found in the RefSeq database:

The AbiH system in Bacteroides faecium (GCF_012113595.1, NZ_CP050831) is composed of 1 protein: AbiH (WP_167962074.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the AbiH is detected in 1225 genomes (5.37 %).

The system was detected in 439 different species.

Proportion of genome encoding the AbiH system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

AbiH

Example 1

Experimental validation

      
graph LR;
    Prevost_1996[Chopin et al., 2005] --> Origin_0
    Origin_0[lactococci 
CAA66252.1] --> Expressed_0[lactococci]
    Expressed_0[lactococci] ----> 936 & c2
    subgraph Title1[Reference]
        Prevost_1996
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        936
        c2
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none

    

References

10.1023/A:1002027321171
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10.1016/j.mib.2005.06.006
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10.1111/j.1574-6968.1996.tb08446.x
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10.1016/j.mib.2023.102312
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