AbiI

Contributors: Florian Tesson

Description

AbiI is a single gene defense system discovered in Lactococcus lactis in 1997 () .

AbiI is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry () . Even though, their name corresponds to an abortive infection, their mechanism of action does not necessarily correspond to an abortive infection. AbiI is classified as an abortive infection in () .

Molecular mechanism

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The AbiI is composed of 1 protein: AbiI.

Here is an example found in the RefSeq database:

The AbiI system in Macrococcus brunensis (GCF_022343725.1, NZ_CP092179) is composed of 1 protein: AbiI (WP_239034930.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the AbiI is detected in 6 genomes (0.03 %).

The system was detected in 6 different species.

Proportion of genome encoding the AbiI system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

AbiI

Example 1

Experimental validation

      
graph LR;
    Chopin_2005[Chopin et al., 2005] --> Origin_0
    Origin_0[lactococcal plasmid 
AAB66882.1] --> Expressed_0[lactococci]
    Expressed_0[lactococci] ----> 936 & c2
    subgraph Title1[Reference]
        Chopin_2005
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        936
        c2
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none

    

References

10.1023/A:1002027321171
no authors
no containerTitle ()
10.1016/j.mib.2005.06.006
no authors
no containerTitle ()
10.1016/S0168-1656(97)01692-1
no authors
no containerTitle ()
10.1016/j.mib.2023.102312
no authors
no containerTitle ()