AbiO

Contributors: Florian Tesson

Description

AbiO is a single gene defense system discovered in 1998 () .

AbiO is one of the so-called "Abi" systems for "Abortive infection" discovered in the 90's in research related to the dairy industry () . Even though, their name corresponds to an abortive infection, their mechanism of action does not necessarily correspond to an abortive infection. AbiO is classified as a possible Abortive infection in () .

This system is only composed of one single gene containing a helicase domain.

Molecular mechanism

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The AbiO is composed of 1 protein: AbiO.

Here is an example found in the RefSeq database:

The AbiO system in Pantoea agglomerans (GCF_004117135.1, NZ_CP034477) is composed of 1 protein: AbiO (WP_129063585.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the AbiO is detected in 100 genomes (0.44 %).

The system was detected in 61 different species.

Proportion of genome encoding the AbiO system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

AbiO

Example 1

Experimental validation

      
graph LR;
    Prevots_1998[Prevots et al., 1998] --> Origin_0
    Origin_0[lactococcal plasmid  
In the plasmid : I61427.1] --> Expressed_0[lactococci]
    Expressed_0[lactococci] ----> 936 & c2
    subgraph Title1[Reference]
        Prevots_1998
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        936
        c2
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none

    

References

10.1023/A:1002027321171
no authors
no containerTitle ()
10.1016/j.mib.2005.06.006
no authors
no containerTitle ()
10.3168/jds.S0022-0302(98)75713-3
no authors
no containerTitle ()
10.1016/j.mib.2023.102312
no authors
no containerTitle ()