Aditi

Contributors: Rachel Lavenir

Description

Aditi was discovered among other systems in 2022 () .

Aditi is composed of two genes: DitA, DitB. Both are of unknown function and have no homology to any known domain. Aditi is named after the Hindu guardian goddess of all life.

Molecular mechanisms

As far as we are aware, the molecular mechanism is unknown.

Example of genomic structure

The Aditi is composed of 2 proteins: DitA and DitB.

Here is an example found in the RefSeq database:

The Aditi system in Streptococcus suis (GCF_003288175.1, NZ_CP025419) is composed of 2 proteins DitB (WP_002937368.1) DitA (WP_002937371.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the Aditi is detected in 40 genomes (0.18 %).

The system was detected in 19 different species.

Proportion of genome encoding the Aditi system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

Aditi

Example 1

Experimental validation

      
graph LR;
    Millman_2022[Millman et al., 2022] --> Origin_0
    Origin_0[Saccharibacillus kuerlensis 
2519017023, 2519017022] --> Expressed_0[Bacillus subtilis]
    Expressed_0[Bacillus subtilis] ----> phi105 & Rho14 & SPP1
    subgraph Title1[Reference]
        Millman_2022
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        phi105
        Rho14
        SPP1
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none

    

References

10.1016/j.chom.2022.09.017
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