Azaca

Example of genomic structure

The Azaca is composed of 3 proteins: ZacA, ZacB and ZacC.

Here is an example found in the RefSeq database:

The Azaca system in Gordonia polyisoprenivorans (GCF_018135605.1, NZ_CP073075) is composed of 3 proteins ZacC (WP_006372053.1) ZacB (WP_006372052.1) ZacA (WP_006372051.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the Azaca is detected in 203 genomes (0.89 %).

The system was detected in 166 different species.

Proportion of genome encoding the Azaca system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

Azaca

Example 1

Experimental validation

      
graph LR;
    Millman_2022[Millman et al., 2022] --> Origin_0
    Origin_0[Bacillus massilioanorexius 
2547646535, 2547646536,
2547646537] --> Expressed_0[Escherichia coli]
    Expressed_0[Escherichia coli] ----> T2 & T4 & T6
    Millman_2022[Millman et al., 2022] --> Origin_0
    Origin_0[Bacillus massilioanorexius 
2547646535, 2547646536,
2547646537] --> Expressed_1[Bacillus subtilis]
    Expressed_1[Bacillus subtilis] ----> SBSphiC
    subgraph Title1[Reference]
        Millman_2022
end
    subgraph Title2[System origin]
        Origin_0
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
        Expressed_1
end
    subgraph Title4[Protects against]
        T2
        T4
        T6
        SBSphiC
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none

    

References

10.1016/j.chom.2022.09.017
no authors
no containerTitle ()