MADS

To do

Example of genomic structure

The MADS is composed of 8 proteins: mad1, mad2, mad3, mad4, mad5, mad6, mad7 and mad8.

Here is an example found in the RefSeq database:

The MADS system in Pseudomonas otitidis (GCF_019879085.1, NZ_CP082244) is composed of 8 proteins mad1 (WP_058876992.1) mad2 (WP_208273447.1) mad3 (WP_208273444.1) mad4 (WP_208273442.1) mad5 (WP_208273440.1) mad6 (WP_208273438.1) mad7 (WP_208273430.1) mad8 (WP_233473447.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the MADS is detected in 72 genomes (0.32 %).

The system was detected in 63 different species.

Proportion of genome encoding the MADS system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

MADS

Example 1

Experimental validation

      
graph LR;
    Maestri_2023[Maestri et al., 2023] --> Origin_0
    Origin_0[Pseudomonas aeruginosa 
WP_058876987.1, WP_058876988.1,
WP_058876989.1, WP_058876990.1,
WP_058876991.1, WP_058876992.1,
WP_124170283.1, WP_201267341.1] --> Expressed_0[Pseudomonas aeruginosa]
    Expressed_0[Pseudomonas aeruginosa] ----> DMS3vir
    subgraph Title1[Reference]
        Maestri_2023
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        DMS3vir
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none

    

References

10.1101/2023.03.30.534895
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