PD-Lambda-2

Example of genomic structure

The PD-Lambda-2 is composed of 3 proteins: PD-Lambda-2_A, PD-Lambda-2_B and PD-Lambda-2_C.

Here is an example found in the RefSeq database:

The PD-Lambda-2 system in Vibrio parahaemolyticus (GCF_013393845.1, NZ_CP040100) is composed of 3 proteins PD-Lambda-2_C (WP_116869984.1) PD-Lambda-2_B (WP_029809306.1) PD-Lambda-2_A (WP_029809305.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the PD-Lambda-2 is detected in 122 genomes (0.54 %).

The system was detected in 59 different species.

Proportion of genome encoding the PD-Lambda-2 system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

PD-Lambda-2

Example 1

Experimental validation

      
graph LR;
    Vassallo_2022[Vassallo et al., 2022] --> Origin_0
    Origin_0[Escherichia coli 
RCO93357.1, RCO93356.1,
RCO93355.1] --> Expressed_0[Escherichia coli]
    Expressed_0[Escherichia coli] ----> LambdaVir & SECphi17 & SECphi18 & SECphi27 & T3
    subgraph Title1[Reference]
        Vassallo_2022
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        LambdaVir
        SECphi17
        SECphi18
        SECphi27
        T3
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none

    

References

10.1038/s41564-022-01219-4
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