PD-Lambda-4

Example of genomic structure

The PD-Lambda-4 is composed of 2 proteins: PD-Lambda-4_A and PD-Lambda-4_B.

Here is an example found in the RefSeq database:

The PD-Lambda-4 system in Serratia sp. LS-1 (GCF_003719595.1, NZ_CP033504) is composed of 2 proteins PD-Lambda-4_B (WP_123061920.1) PD-Lambda-4_A (WP_123061921.1)

Distribution of the system among prokaryotes

Among the 22,803 complete genomes of RefSeq, the PD-Lambda-4 is detected in 69 genomes (0.3 %).

The system was detected in 14 different species.

Proportion of genome encoding the PD-Lambda-4 system for the 14 phyla with more than 50 genomes in the RefSeq database.

Structure

PD-Lambda-4

Example 1

Experimental validation

      
graph LR;
    Vassallo_2022[Vassallo et al., 2022] --> Origin_0
    Origin_0[Escherichia coli 
RCP47953.1, RCP47952.1] --> Expressed_0[Escherichia coli]
    Expressed_0[Escherichia coli] ----> T4 & LambdaVir & SECphi27 & T7
    subgraph Title1[Reference]
        Vassallo_2022
end
    subgraph Title2[System origin]
        Origin_0
end
    subgraph Title3[Expression species]
        Expressed_0
end
    subgraph Title4[Protects against]
        T4
        LambdaVir
        SECphi27
        T7
end
    style Title1 fill:none,stroke:none,stroke-width:none
    style Title2 fill:none,stroke:none,stroke-width:none
    style Title3 fill:none,stroke:none,stroke-width:none
    style Title4 fill:none,stroke:none,stroke-width:none

    

References

10.1038/s41564-022-01219-4
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